16 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
disease (MCTD), Drug-induced ... Idiopathic Arthritis ... #Antinuclear #Antibodies ... ANA #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... erythematosus ( ... , Drug-Induced Lupus ... ANA #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... : - Arthritis ... SLE-Related Auto-Antibodies ... : Drug-induced lupus ... #Erythematosus
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Erythematosus ... • Arthritis domain ... Highly specific antibodies ... #Erythematosus ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... extremities Drug ... 1, SCL-70, RNP antibodies ... • Antihistone: Drug ... #Diagnosis #Rheumatology
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
- Differential Diagnosis ... Suggestive of: Lupus ... not be seen try focus ... gabrieltalledop #dermatology ... #differential #diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Constitutional symptoms, Arthritis ... Erythematosus ( ... sle #comparison #table ... diagnosis #management
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
angiitis induced by drugs ... - systemic lupus ... erythematosus ... #Rheumatology # ... Diagnosis
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... SLE (60-70%) & drug-induced ... #erythematosus ... #diagnosis #rheumatology ... #table #ANA
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus ... erythematosus [ ... ) • Sepsis • Drug-induced ... thrombocytopenia • Liver ... Activation #Syndrome #Diagnosis