19 results
Diagnosis of Cryoglobulinemia Vasculitis

1) Presence of cryoglobulin 
Circulating immunoglobulins that precipitate with cold temperature and dissolve
Vasculitis 1 ... 3 types 2) Vasculitis ... Hyperviscosity syndrome ... arthritis • Renal ... #Rheumatology #
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
vasculitis - Diagnosis ... vasculitis Clinical ... with purpura - Renal ... neuropathy Treatment ... #Vasculitis #Rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
the Skin - Differential ... drug eruptions, paraneoplastic ... Urticarial/LCV) - Cryoglobulinemic ... Disease • Cogan syndrome ... #dermatology #rheumatology
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Pulmonary Renal ... - Differential ... ANCA Associated Vasculitis ... Complement Levels: SLE, Cryoglobulinemic ... #Differential #
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... ANCA-positive vasculitis ... ANCA-negative vasculitis ... Behcet disease, Cryoglobulinemia ... #Syndrome #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... pulmonary and renal ... ANCA +MPO) • Cryoglobulinemic ... • Urinalysis (Renal ... #rheumatology #
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... /HSP • Cryoglobulinemia ... #rheumatology #
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Mnemonic C - Cryoglobulinemia ... antiphospholipid syndrome ... Erythematosus (total 50, renal ... Mnemonic #diagnosis #differential ... #hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
capillary leak syndrome ... • Schnitzler syndrome ... • Cryoglobulinemia ... Renal-centered ... #Diagnosis #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Immunotactoid GN & Cryoglobulinemic ... Autoimmunity: • -MM/WM: Vasculitis ... (Cryoglobulinemic ... vascular beds-renal ... #Monoclonal #Differential