54 results
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Inflammatory Cascade ... engulf foreign pathogens ... System: opsonize pathogen ... cell activity #Inflammatory ... #Inflammation #pathophysiology
Multi-System Inflammatory Syndrome in Children (MIS-C) vs. Kawasaki Disease
CDC Case Definition for MIS-C;
 • < 21
Multi-System Inflammatory ... Kawasaki Disease CDC ... years old with fever ... #MultiSystem #Inflammatory
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
as part of the inflammatory ... response to a pathogen ... hypothalamus → fever ... PATHOPHYSIOLOGY: ... Synthesis of pro-inflammatroy
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
Inflammatory Joint ... Differential Diagnosis Algorithm ... • Rheumatic Fever ... • Rheumatic Fever ... Differential #Diagnosis #Algorithm
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
mutation) that alter inflammatory ... GCA is almost never ... /Symptoms: - Fever ... Temporal #Arteritis #Pathophysiology
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Inflammatory mechanism ... dendritic cell (DC ... activate naive CD4 ... #asthma #pathophysiology ... #inflammatory #
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic Algorithm ... Pathophysiology ... - Pathophysiology ... instability - New-onset fever ... Color #Targetoid #Algorithm
Causes of Acute Onset Fever - Differential Diagnosis Algorithm
Viral:
 • Rhinovirus
 • Influenza Virus
 • Parainfluenza
of Acute Onset Fever ... Differential Diagnosis Algorithm ... • Extremity Inflammatory ... #Fever #Acute ... Differential #Diagnosis #Algorithm
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Fever of Unknown ... Refer to your ‘Fever ... Returning Traveler’ algorithm ... respective fungal pathogens ... udaygulati #FUO #Fever
Immune Reconstitution Inflammatory Syndrome (IRIS) - Pathophysiology
Risk factors:
 - Low CD4 count
 - Disseminated OI
 -
Reconstitution Inflammatory ... Syndrome (IRIS) - Pathophysiology ... factors: - Low CD4 ... Restoration of exuberant pathogen-specific ... Syndrome #IRIS #Pathophysiology