16 results
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
is rare Normal complement ... response: The complement ... response to bacterial pathogens ... tissue -> Fatigue, fever ... #pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... staining): • Low Complement ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Gonorrhea: Pathophysiology

 - Neonatal Transmission -> Direct contact of patient mucosa with mother's infected mucosa while
Gonorrhea: Pathophysiology ... eradication of pathogen ... Pathogen cleared ... antibodies and causes ... activation of complement
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Algorithmic Approach ... triad (<10%): fever ... sterile pyuria, WBC casts ... eosinophiluria, microscopic ... Nephritis #AIN #Algorithm
Causes of Dysuria - Differential Diagnosis Algorithm
Pyuria - Leukocytes on Dipstick/Microscopy
 - Bacteriuria & Hematuria -
Differential Diagnosis Algorithm ... Leukocytes on Dipstick/Microscopy ... Leukocytes on Dipstick/Microscopy ... Neoplasm - Non-Pathogenic ... Differential #Diagnosis #Algorithm
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Differential Diagnosis Algorithm ... • Exercise • Fever ... polyangiitis (GPA) / microscopic ... Differential #Diagnosis #Algorithm
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
Differential Diagnosis Algorithm ... • Rheumatic Fever ... polyangiitis (GPA)/microscopic ... • Rheumatic Fever ... #Orthopedics #Causes
Pathogenesis of Rheumatic Fever

Pathogenesis of rheumatic fever. 
1. GAS pharyngitis leads to antigenic presentation of pathogenic
Pathogenesis of Rheumatic Fever ... Pathogenesis of rheumatic fever ... presentation of pathogenic ... antibodies which can cause ... #Pathophysiology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... Red Flags: • Fever ... Sjogren's, GPA, EGPA, Microscopic ... #Causes #dermatology
Cyclosporiasis - Diagnosis and Management Summary
Pathogen: 
 • Cyclospora cayetanensis
 • Foodborne, waterbone, and soil-transmitted.
 •
Management Summary Pathogen ... • Anorexia, Nausea ... diarrhea, Low-grade fever ... Established via stool microscopy