9 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
hemolytic anemia ... thrombocytopenic purpura ... uremic syndrome (HUS ... #Causes #differential ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
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Hemolysis - Differential ... Diagnosis Algorithm ... anemia • ... MAHA (TTP, DIC, HUS ... Differential #Diagnosis
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... syndrome (ST-HUS ... Drug-induced thrombotic microangiopathy ... anemia" • HELLP ... #diagnosis #hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
(TMA) - Differential ... Diagnosis Table ... Thrombocytopenic Purpura ... #TMA #hematology ... diagnosis #HUS
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
hemolytic anemia ... and laboratory diagnosis ... hemolytic anemia ... #hemolytic #anemia ... #Hematology #Pathology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... mortality, and first-line ... thrombocytopenic #purpura ... thrombocytopenia #Comparison #Diagnosis ... #Table #Hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... IVIG infusion Intravascular ... • MAHA: TTP, HUS ... #Anemia #Differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic ... anemia - Splenomegaly ... Diagnosis #hematology ... #nonpalpable #dermatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
Thrombocytopenic Purpura ... reflection of intravascular ... anemia Indirect ... WBC count and differential ... #Workup #Hematology