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diagnosis differential algorithm anemia clinical workup blood analysis anemias bacilliformis bands ehrlichia ewingii fever interpretation laboratory maha management metamyelocytes microangiopathic
Laboratory Testing in Hemolytic Anemia Intravascular vs Extravascular Hemolysis Reticulocytes Unconjugated bilirubin LDH Peripheral smear Haptoglobin Urine hemosiderin Urine hemoglobin Carboxyhemoglobin #Hemolytic #Anemia #Laboratory #Testing #workup
Laboratory Testing in Hemolytic ... Extravascular Hemolysis ... bilirubin LDH Peripheral ... smear Haptoglobin ... #hemolysis
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Reticulocytes • Abnormal peripheral ... smear Immune-mediated ... Hemolysis: • ... Diagnosis #Algorithm #hematology
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic ... Microangiopathic hemolytic ... microangiopathic #hemolytic ... #Pathology #Smear ... #Microscopy
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood ... Microangiopathic hemolytic ... Microspherocytes: Autoimmune hemolytic ... Analysis #hematology ... #microscopy #interpretation
How to distinguish a metamyelocyte from a band neutrophil. - Kyle Bradley, MD @KyleBradleyMD #Clinical #Pathology #Microscopy #Blood #Smear
KyleBradleyMD #Clinical #Pathology ... #Microscopy #Blood ... #Smear #Peripheral ... #Neutrophils #Comparison
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Malaria, Babesiosis, Bartonella ... Dehydrogenase ↑ - Peripheral ... Blood Smear ↑ abnormal ... Urobilinogen #Hemolysis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hemorrhage and hemolysis ... intravascular hemolysis ... blood smear - Shows ... out an immune hemolytic ... the severity of hemolysis
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
BMP, uric acid, peripheral ... smear, reticulocyte ... ↑ Destruction (hemolysis ... Diagnosis #Algorithm #hematology
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Oroya Fever Hematologic ... disease caused by Bartonella ... lysis → severe hemolytic ... • Acute phase: Peripheral ... smear - Cocci &
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm Peripheral ... Smear concerning ... → Refer to hematology ... • Nonmalignant hematologic ... blood loss, Acute hemolysis
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