10 results
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Cell Disease - Pathophysiology ... shape, HbS induces RBC ... This leads to RBC ... #Complications ... #Hematology #Sequelae
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
- Arthralgia, Arthritis ... Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... #pathophysiology
hematopoiesis - leukocyte maturation tree

- Amy Chung, MD, MSc @AmyChung 

#hematopoiesis #leukocytes #maturation #tree #pathophysiology #Hematology
Amy Chung, MD, MSc ... maturation #tree #pathophysiology ... #Hematology #Progenitor ... #Cells #WBC #pathology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
• Inflammatory arthritis ... Noninflammatory arthritis ... Enthesitis: • Site of pathology ... #Joint #Pain #MSK ... #rheumatology #
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Signs/Symptoms/Complications ... weight-bear • Arthritic ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology
Knee Effusions - Arthrocentesis Interpretation

Inflammatory arthritis:
 • Color: Yellow-> Green
 • Clarity: Opaque
 • Viscosity: Low
Inflammatory arthritis ... Viscosity: Low • WBC ... : Variable • WBC ... analysis: • MSU ... membrane histo-anthology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Lyme), reactive arthritis ... SLE, psoriatic arthritis ... #Joint #Pain #MSK ... #rheumatology # ... differential #diagnosis #arthritis
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
findings Skeletal Pathology ... of the Hip • Arthritis ... Trendelenburg #Gait #pathophysiology ... signs #diagnosis #msk
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
to Joint Pain - Arthritis ... , erythema and WBC ... #Arthritis # ... Differential #Diagnosis #MSK ... #rheumatology #
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: Complications ... bone formation MSK ... to breakage -> Pathologic ... PagetsDisease #pathophysiology ... signs #symptoms #complications