62 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... organ damage • Treatment ... Lysis Syndrome: • Pathophysiology
Causes of Aplastic Anemia

#Aplastic #Anemia #Causes #Pathophysiology #Pathology #Treatment #Management #Differential
Anemia #Causes #Pathophysiology ... #Pathology #Treatment
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
One allele of RB1 ... One allele of RB1 ... Retinoblastoma Signs / Symptoms ... Retinoblastoma #pathophysiology ... diagnosis #signs #symptoms
Lower Urinary Tract Infection: Pathogenesis and Clinical Findings

- Predisposing Factors:  Immunocompromised state, diabetes, elderly, female
epithelium and causing symptoms ... Signs/Symptoms ... Malaise, Incr WBC ... UrinaryTractInfection #LUTI #Pathophysiology ... #Signs #Symptoms
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
incidentally via CBC ... When present, symptoms ... • "Vasomotor" symptoms ... • Treatment is ... the reduction of symptoms
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Cell Carcinoma (RCC ... Symptoms of metastatic ... disease Imaging and Treatment ... pain and ↑ ALP RCC ... Hb levels and CBC
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... if high risk if WBC ... Diagnosis: >3 symptoms ... Renal Failure Treatment
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Biliary Cirrhosis (PBC ... ) - Summary PBC ... 30-65 years PBC ... Pathophysiology ... Signs and Symptoms
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment
Stop offending agents:
 • List as allergies
Eosinophilia and Systemic Symptoms ... DRESS) Syndrome Treatment ... monitoring: • CBC ... DRESS #Syndrome #Treatment
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
biliary cirrhosis (PBC ... (SLE) Signs / Symptoms ... Sjogrens #Syndrome #Pathophysiology ... Diagnosis #Signs #Symptoms