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hematology algorithm agglutinin antibody autoimmune causes classification cold disease fever hemolysis hodgkins infectiousdiseases lymphoma maha microangiopathic microscopy oncology platelets rheumatology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Anemia 1) DIAGNOSE ... type ± C3d • Blood ... smear: Differential ... #Anemia #diagnosis ... #management #treatment
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... - Differential ... • Peripheral blood ... smear + DAT + further ... #Anemia #Differential
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... anemia. ... and laboratory diagnosis ... arrow) Peripheral smear ... #Pathology #Smear
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... Defects: Sickle cell anemia ... - Peripheral Blood ... Smear ↑ abnormal
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Diagnosis: • hemolytic ... Immunoglobulin M (IgM) • Blood ... smear - RBC agglutination ... younger pts) Differential ... sensitize red blood
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... of Peripheral blood ... smear - Shows schistocytes ... anemia Indirect ... WBC count and differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... Peripheral Smear ... hematologic: Acute blood ... loss, Acute hemolysis ... , deficiency anemia
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... nodosum • Immune hemolytic ... anemia • Pain ... Immunohistochemical studies (to differentiate ... hematology #oncology #management
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
No hemolytic anemia ... cases of malaria diagnosed ... renal function • Blood ... a chest film; blood-smear ... Fever #Travel #Differential
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