9 results
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Antibody Autoimmune Hemolytic ... Anemia 1) DIAGNOSE ... reticulocytes • Hemolysis ... smear: Differential ... #Anemia #diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... Immune mediated hemolysis ... Microangiopathic hemolytic ... UnremarkableLab #Hemolytic ... #Anemia #Differential
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... microangiopathic hemolytic ... Microangiopathic hemolytic ... microangiopathic #hemolytic ... #Pathology #Smear
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Defects: Sickle cell anemia ... - Peripheral Blood ... Smear ↑ abnormal ... Urobilinogen #Hemolysis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
hemorrhage and hemolysis ... intravascular hemolysis ... of Peripheral blood ... out an immune hemolytic ... the severity of hemolysis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Diagnosis: • hemolytic ... • Compensated hemolysis ... smear - RBC agglutination ... intravascular hemolysis ... agglutinin #disease #hemolytic
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... Peripheral Smear ... hematologic: Acute blood ... loss, Acute hemolysis ... , deficiency anemia
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... nodosum • Immune hemolytic ... anemia • Pain ... Immunohistochemical studies (to differentiate ... hematology #oncology #management
Fever After International Travel

Infectious Disease:
• Endemic in either the destination or home region

Viral Syndromes:
Arboviral infections, a
No hemolytic anemia ... cases of malaria diagnosed ... renal function • Blood ... a chest film; blood-smear ... Fever #Travel #Differential