20 results
Chronic Neutrophilic Leukemia (CNL)

 • Signaling Pathway
 • WHO Dx Critera
 • Risk Stratification
 • Treatment
Chronic Neutrophilic ... Pathway • WHO Dx Critera ... Stratification • Treatment ... #Leukemia #diagnosis ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... ALL Symptoms: ... ) CLL Symptoms: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... with no early symptoms ... microglobulin Treatment ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... minimal tumor burden Diagnosis ... #Chronic #Lymphocytic ... #Leukemia #oncology ... #hematology #hemeonc
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... in those with CLD ... months without treatment ... #Hepatology #gastroenterology ... #management #diagnosis
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... ARDS to explain symptoms ... : 33% • Treatment ... : No • Treatment ... #diagnosis #comparison
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... • Induce blast cell ... : >3 symptoms, or ... #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... pattern of spread, B symptoms ... Responsive to Treatment ... Classification #pathophysiology ... #Hematology #Diagnosis
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... : Chronic heart ... and iron release Diagnosis ... functional ID) Treatment ... improvement in symptoms
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
neuropsychiatric symptoms ... Prevalence: At cirrhosis ... TIPS West Haven Criteria ... #Management #treatment ... #hepatology