8 results
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... of Hypocomplementemic ... Complex Formation - Complement ... Pathway Activation ... Vasculitis #HUV #Pathophysiology
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
-10000x higher in ... deficiency than in ... pathway is a non-specific ... alternative, or lectin pathway ... #pathophysiology
The interferon (IFN) signature: what’s the point? How to use it in clinical practice?

Characterizing activity of
The interferon (IFN ... Characterizing activity of IFN ... pathway in the ... understanding of pathophysiology ... To propose new classifications
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
activation • Complement ... tagged with C3 complement ... the classical pathway ... (see Complement ... Humoral #Immunity #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
are deposited in ... Complement activation ... Hypersensitivity #Types #Classification ... #Pathophysiology ... Diagnosis #Reactions #Table
Antibiotic classification refers to the categorization of antibiotics based on their chemical structure, mechanism of action,
Antibiotic classification ... of antibiotics in ... the metabolic pathways ... #pharmacology #classification ... #table
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
that precipitate in ... immune complexes in ... Through 2 Different Pathways ... • Low serum C4 complement ... diagnosis #types #classification
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
If untreated ... rapid decline in ... guide subtype classification ... tubulopathy) - Complement ... pathway activation