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diagnosis ana rheumatology antibody alopecia antibodies causes cytoplasmic dermatology hairloss nuclear pulmonary abnormal classification ctchest cystic dcld disease disorders enzymes
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
and Cytoplasmic Patterns ... Nuclear Patterns ... • Homogeneous pattern ... cases) • Speckled pattern ... • Centromere pattern
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Patterns Homogeneous ... pattern: • SLE ... cases) Speckled pattern ... Ku Centromere pattern ... #Nuclear #Patterns
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
serial dilution, a pattern ... significant • Pattern ... : The ANA patterns ... not specific ANA Patterns ... Antibodies #ANA #patterns
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... • Nucleolar: Diffuse ... Kumfer @AnnKumfer #Antinuclear ... Antibodies #ANA #patterns ... rheumatology #diagnosis #differential
Algorithm for nodular pattern The algorithm to distinguish perilymphatic, random and centrilobular nodules is the following: - Look
pattern The algorithm ... are visible, the pattern ... the nodules are diffuse ... NodularPattern #Nodular #Pattern ... MultipleNodules #Nodules #Differential
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Antinuclear Antibody ... Testing Cytoplasmic ... Patterns Reticular ... #Cytoplasmic #Patterns ... #differential #
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
and Focal) Differential ... Diagnosis Algorithm ... planopilaris Pattern ... #dermatology #Differential ... #Diagnosis #Algorithm
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
to Headaches - Differential ... Diagnosis Algorithm ... PHANTOMS): • Pattern ... #Diagnosis #Algorithm ... neurology #PHANTOMS #mnemonic
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... Diagnosis Algorithm ... lymphadenopathy more diffuse ... involvement, irregular pattern ... #algorithm
Diffuse Hair Loss (Alopecia) - Differential Diagnosis Algorithm Scarring - Irreversible-biopsy required • Lupus erythematosus • Lichen
Diffuse Hair Loss ... (Alopecia) - Differential ... Diagnosis Algorithm ... planopilaris Pattern ... #Diagnosis #Algorithm
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