46 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
SyndromeClinically ... disorders • Diagnosis ... and Treatment Algorithm ... #Hematology #eosinophilia ... #eosinophils #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... only curative treatment ... #Management #treatment ... #hematology #oncology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... eosinophilia (common causes ... glucocorticoid treatment ... #Differential #diagnosis ... #hematology #eosinophilia
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... - Differential Diagnosis ... Leukemia - Primary Hypereosinophilic ... Syndrome - Chronic ... #Causes #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia ... Syndrome (HES) ... than 1500 and clinical ... eosinophilia Secondary Causes ... #hematology #differential
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
based primarily on clinical ... assessment, however ... Estimates of the clinical ... and to adjust treatment ... #Hematology #HIT
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... - Differential Diagnosis ... capillary leak syndrome ... • Schnitzler syndrome ... #hematology #oncology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Causes of false- ... amyloidosis Other causes ... plasmacytoma, POEMs syndrome ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... by a hemophilia treatment ... though safety assessment ... #Management #treatment ... #hematology
When to look for clonal/neoplastic hypereosinophilia (HEo)?
 - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
clonal/neoplastic hypereosinophilia ... Exclusion of frequent causes ... ) - Clinical symptoms ... #HEON #Diagnosis ... #Signs #Hematology