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diagnosis syndrome disease hlh lymphohistiocytosis anemia aplastic oncology activation adultonset apml capillary clarksons dermatology diagnossi differentiation kawasaki kd leak macrophage
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... : • Infection ... rapidly, and empiric antibiotic ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
: • Recurrent infections ... megaloblastic anemia Treatment ... (transfusions, antibiotics ... Anemia #diagnosis #management ... #treatment #hematology
Kawasaki Disease (KD) - Diagnosis and Management Summary Kawasaki Disease (KD) is the most common vasculitis of
Diagnosis and Management ... cæxist with other infections ... KD #vasculitis #rheumatology ... #pediatrics #diagnossi ... #management #treatment
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Diaqnoses: • Infectious ... hepatitis • Pulmonary ... Disease #diagnosis #management ... #treatment #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
Hemophagocytic Lymphohistiocytosis ... (HLH) Treatment ... associated with infection ... EricsMedicalLectures/ #HLH #Hemophagocytic ... #management #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
A subset of hemophagocytic ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... Differential Diagnosis: Infection ... APML #diagnosis #management ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
- β-lactam antibiotics ... Idiopathic • Infections ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
causes such as infectious ... and lower jaw Treatment ... syndrome with acne: antibiotics ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
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