12 results
leukemia causes lymphocytic mds myelodysplastic aplastic apml classification differentiation hemeonc hodgkins immunodeficiency immunology lymphoma myelodysplasia neutropenia platelets thrombocytosis variable workup
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
autoimmune hemolytic anemia ... : • Nephrotic syndrome ... syndrome, HIV) ... #immunology #hematology ... #diagnosis #management
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Diagnosis Algorithm ... ITP • SLE • CLL ... Non-lmmune: • HELLP Syndrome ... Diagnosis #Algorithm ... #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
: • Most common ... , thrombocytopenia ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... Kawasaki, Nephrotic syndrome ... : Chronic infections ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Complications: 1) Infection ... due to hypogammaglobulinemia ... #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... Myelodysplastic #Syndrome ... #Management #treatment ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... , thrombocytopenia ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Most common cytopenia ... Marrow Failure • Chronic ... blood count with differential ... #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... #oncology #hematology ... #diagnosis #management
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... Infant/child: - Infection-common ... ambulatory patients - Infections-common ... #hematology
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