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causes oncology syndrome anemia hemophagocytic lymphohistiocytosis pancytopenia workup blood classification gastroenterology hemolytic hodgkins lymphoma mcv product reactions signs summary symptoms
Diagnostic Schema for Hyperferritinemia Pearl: Diseases associated with extreme elevations: 1. HLH 2. Still's disease 3. Systemic
Diagnostic Schema ... HLH 2. ... Hyperferritinemia #Algorithm ... #Differential # ... Diagnosis #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... Rebound effect from treatment ... #Diagnosis #Algorithm ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... Myelofibrosis Infectious ... effect following treatment ... #Diagnosis #Algorithm ... #Causes #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diagnosis Congenital ... Diseases: • GATA2 ... erythematosus • HLH ... deficiency Infections ... #Diagnosis #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... : • Infection ... agent are the main ... #management #treatment ... #hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
Haematology - ... Rheumatology ... #Limping #NWB #Algorithm ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Diagnosis Algorithm ... HLH syndrome 5. ... Metastatic Disease ... #Diagnosis #Algorithm ... #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Adult-onset Still disease ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Diagnosis Algorithm ... Alloimmune • anti-HLA ... Vasculitis • Infection ... #Diagnosis #Algorithm ... #Causes #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Diagnosis Algorithm ... HLH syndrome 5 ... Metastatic Disease ... #Diagnosis #Algorithm ... #Hematology
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