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oncology algorithm leukemia approach basophils classification cll diffuse eosinophil eosinophilia gap globulin hodgkins isolated joint lad lymphadenopathy lymphocytic lymphoma management
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... Myeloproliferative Disorders ... : • Chronic myeloid ... Diagnosis #causes ... #hematology #basophils
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Neutropenia - Differential ... Antineoplastic Viral Infection ... Idiopathic - Chronic ... • Rheumatoid Arthritis ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential ... Myelofibrosis Infectious ... • Rheumatic disorders ... effect following treatment ... #Causes #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... • Rheumatoid Arthritis ... Leukemia - History of Bleeding ... Age > 50 • Chronic ... #Causes #Hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Causes of Neutropenia ... - Differential ... hypertension and/or drug treatment ... diagnosis #causes ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... Diagnosis and Workup ... procedures - Infection ... Diagnosis #Causes ... #Workup #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... evaluation or workup ... glucocorticoid treatment ... #Algorithm #Differential ... #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... eosinophilia, basophilia ... or functional neutropenia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
to Joint Pain - Diagnostic ... Joint #Pain #MSK #rheumatology ... #approach #workup ... #differential # ... diagnosis #arthritis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
weeks without infection ... Cytopenias: • Neutropenia ... microglobulin Treatment ... #workup #oncology ... #hematology
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