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algorithm oncology management basophilia basophils classification cll eosinophil eosinophilia essential hodgkins leukemia lymphocytic lymphoma mds myelodysplasia myelodysplastic platelets secondary syndromes
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... ): • Acute infection ... thrombocythemia (ET ... Diagnosis #Causes ... #hematology #secondary
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Myelofibrosis Infectious ... • Rheumatic disorders ... effect following treatment ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Rebound effect from treatment ... : Chronic infections ... #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... are asthma, allergy ... glucocorticoid treatment ... #Algorithm #Differential ... #diagnosis #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Causes of Neutropenia ... - Differential ... hypertension and/or drug treatment ... diagnosis #causes ... #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
released during an allergic ... Myeloproliferative Disorders ... : • Chronic myeloid ... #Diagnosis #causes ... #hematology #basophils
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
Diagnosis Framework ... Eosinophilic GI Disorders ... • Parasitic infections ... #Diagnosis #hematology ... #allergy
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
) ET is a chronic ... Most cases are related ... hemoproliferative disorder ... #hematology #diagnosis ... #management #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
weeks without infection ... Cytopenias: • Neutropenia ... microglobulin Treatment ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Marrow Failure • Chronic ... Myeloproliferative Disease • Neutropenia ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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