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causes algorithm management oncology anemia leukemia thrombocytosis workup blood chronic classification cll disease lymphocytic platelet platelets product purpura reactions activation
Bleeding disorders in children #Bleeding #Disorders #Differential #Hematology #Pediatrics #Peds
Bleeding disorders ... in children #Bleeding ... #Disorders #Differential ... #Hematology #Pediatrics ... #Peds
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... Thrombocytopenia ... #Bruising #Differential ... #Causes #Hematology
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
disorder Clinical ... • Easy bruising ... factor VIII) Treatment ... VonWillebrand #Disease #Diagnosis ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... microangiopathy: Thrombotic thrombocytopenic ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology
Thrombocytopenia - Differential Diagnosis Algorithm Decreased production: • Bone marrow suppression • Bone marrow failure • Bone
Thrombocytopenia ... - Differential ... infiltration • Infection ... Connective tissue disorders ... #hematology #platelets
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Myelofibrosis Infectious ... • Rheumatic disorders ... effect following treatment ... following EtOH induced thrombocytopenia ... #Causes #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... DIC/TTP/HUS - Hemolytic ... #Diagnosis #hematology ... #rheumatology #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... Diagnosis and Workup ... - History of bleeding ... procedures - Infection ... #Workup #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Schistocytes, thrombocytopenia ... inclusions - If infection ... Consider RBC membrane disorder ... #workup #hematology
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