26 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
- Arthralgia, Arthritis ... Myopathy (Also caused ... Erythematosus #SLE #MSK ... Complications #pathophysiology ... #signs #symptoms
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
weight-bear • Arthritic ... Leg • Shooting pains ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology ... #signs #symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... tract, and often causes ... Presentation - Systemic Symptoms ... purpura: strong sign ... , testes -> pain
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Viral replication causes ... Non-specific abdo pain ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
Raise Test - Pain ... MeralgiaParesthetica #MSK ... #pathophysiology ... #differential # ... diagnosis #signs
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... lumbar spine Signs ... CaudaEquina #Syndrome #MSK ... #pathophysiology ... #signs
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... blood vessels (vasculitis ... inflammation tends to cause ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
of the Hip • Arthritis ... Sacroiliac Joint Pain ... #causes #symptoms ... #signs #diagnosis ... #msk
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
Colicky abdominal pain ... Arthralgia's (common), arthritis ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... burning sensation or pain ... : • Petechiae ... reticularis Differential ... • Giant cell arteritis