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hematology dermatology cardiology causes endocarditis oncology petechiae activation adultonset anemia antinxp2 antinxp2dm aplastic coagulation criticalcare dermatomyositis dic disseminated infectiousdiseases intravascular
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH These rashes can be especially challenging and are associated with devastating differential
, an algorithmic ... in vasculitic diseases ... disseminated gonococcal disease ... or purpuric rash ... Purpural #Purpuric #Rash
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
- Diagnostic Algorithm ... commonly renal and pulmonary ... Dermatology #Rash ... #Differential # ... Ddxof
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... erythroderma, petechiae ... Maculopapular #Scaling #Color ... #Differential # ... Ddxof
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
arthritis, Skin rash ... fraction < 20% Differential ... hepatitis • Pulmonary ... #diagnosis #management ... #treatment #rheumatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... disorders • Celiac disease ... effect following treatment ... following EtOH induced thrombocytopenia ... #Diagnosis #Algorithm
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Manifestations of DIC: • Petechiae ... • Severe Liver Disease ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
Shock - Differential ... , Severe Valve Disease ... • Obstructive: Pulmonary ... #algorithm #treatment ... #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
mucosal bleeding (Petechial ... or purpuric rash ... Treatment: • Corticosteroids ... #Management #Hematology ... #Rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin color ... infections/fevers • Thrombocytopenia ... bleeding, and petechiae ... aplastic anemia Treatment ... #diagnosis #management
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Cerebral > Splenic, pulmonary ... hemorrhages • Petechiae ... Marantic (NTBE) Differential ... Regurgitation • Colon ... #management #cardiology
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