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oncology causes anemia chronic classification lymphocytic management pancytopenia petechiae thrombocytosis basophilia cancer dermatologic enlarged eosinophil eosinophilia erythematosus gap globulin gpa
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... Diagnosis Framework ... Myeloproliferative Disorders ... Colitis and Crohn’s Disease ... #hematology #basophils
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Diagnosis Algorithm ... lymphadenopathy, petechiae ... #Diagnosis #Algorithm ... #hematology #WBC ... #Leukemoid
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... • Rheumatic disorders ... • Celiac disease ... #Diagnosis #Algorithm ... #Causes #Hematology
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH These rashes can be especially challenging and are associated with devastating differential
in vasculitic diseases ... or purpuric rash ... While all patients ... #Diagnosis #Dermatology ... Purpural #Purpuric #Rash
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Rash - Differential ... Diagnosis Algorithm ... #Petechiae #Rash ... Diagnosis #Algorithm ... #Causes #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... eosinophilia, basophilia ... Significant ↓ PLT: Petechiae ... #Hematology #Oncology ... #Diagnosis
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Diagnosis Algorithm ... • Lymphoma • Leukemia ... Myeloproliferative disorders ... #Diagnosis #Algorithm ... #Causes #Hematology
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
chronic kidney disease ... Probable bone marrow disorder ... #hematology #diagnosis ... #differential # ... workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... lymphoproliferative disorders ... microglobulin Treatment ... #diagnosis #workup ... #oncology #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... thalassemia, S Lepore • Basophilic ... Consider RBC membrane disorder ... #Diagnosis #Algorithm ... #workup #hematology
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