19 results
oncology algorithm causes anemia blood cll comparison leukemia lymphocytic product reactions rheumatology syndrome thrombocytosis vonwillebrand workup acquired atlas atopic atopy
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
• Rheumatic disorders ... • Celiac disease ... effect following treatment ... following EtOH induced thrombocytopenia ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... microangiopathy: Thrombotic thrombocytopenic ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
inherited bleeding disorder ... bruising • Skin ... platelet count (mild thrombocytopenia ... factor VIII) Treatment ... #Diagnosis #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... Schistocytes, thrombocytopenia ... Consider RBC membrane disorder ... #workup #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... DIC/TTP/HUS - Hemolytic ... #Diagnosis #hematology ... #nonpalpable #dermatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... Rebound effect from treatment ... • Infections: Chronic ... #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
deficiency anemia, Chronic ... Microangiopathic Hemolytic ... Unstable hemoglobin disorders ... RBC #Morphology #differential ... #diagnosis #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... and Management ... thrombocythemia), Autoimmune disease ... #Management #treatment ... #hematology #differential
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... leukemia in adults • Disorder ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology ... #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... specifically immune thrombocytopenia ... and autoimmune hemolytic ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
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