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oncology algorithm differential workup causes classification cll myelodysplastic pancytopenia syndrome activation approach common cvid hemeonc hodgkins hypogammaglobulinemia immunodeficiency immunology lymphoma
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... in adults • Disorder ... #Lymphocytic #Leukemia ... #oncology #hematology ... #management
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... or acute leukemia ... #Anemia #diagnosis ... #management #treatment ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Myelogenous Leukemia ... • Rheumatic disorders ... • Celiac disease ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Deficiency • Aplastic ... of Chronic Disease ... - Acquired ... Algorithm #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Hepatomegaly • Skin ... • Neutropenia, anemia ... #Lymphocytic #Leukemia ... #oncology #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... transformation to acute leukemia ... Myelodysplastic #Syndrome #MDS ... #Diagnosis #Management ... #treatment #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Cytogenetics and FISH • Acquired ... Aplastic Anemia ... • Hypoplastic MDS ... Metastatic Disease ... #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Cytogenetics and FISH • Acquired ... Aplastic Anemia ... • Hypoplastic MDS ... Metastatic Disease ... #Algorithm #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... - infiltrates (anemia ... #Hematology #Oncology ... #Diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... anemia Treatment ... #hematology #diagnosis ... #management
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