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oncology lymphocytic thrombocytosis anemia approach basophilia basophils enlarged eosinophil et gap globulin hemeonc hodgkins lymphoma lymphomas lymphoproliferative mds myelodysplasia myelodysplastic
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... Myelogenous Leukemia ... • Celiac disease ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Diagnosis Algorithm ... • Lymphoma • Leukemia ... Myeloproliferative disorders ... #Diagnosis #Algorithm ... #Causes #Hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... symptoms (eg, skin ... #Disorders #Algorithm ... #Differential # ... diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
inflammatory disorders ... Thrombocytosis): • Essential ... myeloid leukemia ... #Diagnosis #Causes ... #hematology #secondary
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Myeloproliferative Disorders ... : • Chronic myeloid ... leukemia (CML) ... #Diagnosis #causes ... #hematology #basophils
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... -> Invade Skin: ... #Hematology #Oncology ... #Diagnosis
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm ... Disease • Marrow ... Non-lmmune #Anemia #Classification ... #Diagnosis #Algorithm ... #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... cells can indicate disease ... microglobulin Treatment ... #Leukemia #diagnosis ... workup #oncology #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential ... Diagnosis Algorithm ... Treated Like Acute Leukemias ... #Classification ... pathophysiology #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... in adults • Disorder ... chemotherapy for low-risk disease ... #hematology #hemeonc ... #diagnosis #management
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