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differential leukemia algorithm anemia blood cll eosinophilia immunology lymphocytic product reactions aplastic atopic atopy basophilia basophils classification common cvid dermatitis
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
(HES) - Diagnosis ... and Management ... Secondary Causes ... : - Allergic disorders ... #diagnosis #hematology
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... - Differential Diagnosis ... Hypereosinophilic Syndrome ... - Chronic Eosinophilic ... #Causes #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... • Rheumatic disorders ... • Celiac disease ... following EtOH induced thrombocytopenia ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... : - Thrombocytopenia ... Kasabach-Merritt syndrome ... #hematology #rheumatology ... #nonpalpable #dermatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... • Acne • Allergy ... Age > 50 • Chronic ... Lymphocytes) - Monoclonal ... #Hematology #Oncology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Causes of false- ... amyloidosis Other causes ... plasmacytoma, POEMs syndrome ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
- Differential Diagnosis ... ESRD & CAD • Eosinophilic ... GI Disorders ... cell activation syndrome ... #hematology #allergy
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
leukemia in adults • Disorder ... chemotherapy for low-risk disease ... fludarabine) 3) Monoclonal ... #hematology #hemeonc ... #diagnosis #management
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... microangiopathy: Thrombotic thrombocytopenic ... lymphoproliferative disorders ... #hematology #anemia
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
released during an allergic ... Myeloproliferative Disorders ... : • Chronic myeloid ... Colitis and Crohn’s Disease ... #causes #hematology
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