11 results
Evaluation abnormal liver tests in pregnancy
- Cholestatic Pattern
- Hepatocellular Pattern

#LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Evaluation abnormal ... Hepatocellular Pattern #LFTs ... obgyn #obstetrics #hepatology ... #diagnosis #differential ... #algorithm
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
Algorithm for workup ... thrombocytopenic purpura/hemolytic ... thrombocytopenia, Hematology ... #Diagnosis #Differential ... #Evaluation
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
Diagnosis Algorithm ... reticulocyte count, LFTs ... ↑ Destruction (hemolysis ... #Diagnosis #Algorithm ... #hematology #workup
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... disease (diverse genotypes ... #Anemia #Differential ... #workup #hematology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver Injury ... 2-5x normal - Hemolysis ... Patterns #Liver #Injury ... #hepatology #LFTs ... transaminitis #differential
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
dose dependent injury ... Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
- Differential ... #Differential # ... Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... Bilirubin: RBC (hemolysis ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... #hepatitis #differential ... #diagnosis #algorithm ... #hepatology
General Approach to Anemia - Differential Diagnosis Framework
1) Check reticulocyte count to determine if hypo/hyper-proliferative
2) Exclude
Approach to Anemia - Differential ... hyper-proliferative 2) Exclude hemolysis ... guide further evaluation ... #diagnosis #hematology ... #algorithm #reticulocyte