13 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
- TTP/HUS, HELLP ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
child * Severe cases ... #TTPHUS #HELLP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... • Wilson's • Pregnancy ... - AFLP, HELLP ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... antiphospholipid syndrome - Pregnancy ... : HELLP - Mechanical ... Diagnosis #Framework #hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
, no necrosis HELLP ... #hepatology #obstetrics ... #hepatitis #comparison ... #differential # ... diagnosis #icp #HELLP
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... biliary obstruction, HELLP ... Toxic: Medication, Pregnancy ... Acute #algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... AP, ↑INR, ↑BUN/Cr ... infiltration) Differential ... Preeclampsia, HELLP ... #hepatology #obstetrics
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
CT #MRI #POCUS #radiology ... #differential # ... diagnosis #comparison ... #table #appearance ... #hepatology
Appearance of Liver Lesions on Computed Tomography (CT) - Arterial Phase, Portal Venous Phase and Delayed
ComputedTomography #CT #radiology ... #differential # ... diagnosis #comparison ... #table #appearance ... #hepatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... fluid balance, and CXR ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table