28 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Inflammatory Conditions: Rheumatologic ... , Vasculitides, ... Diagnosis #Algorithm #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... RBC's secondary to platelet ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology ... #rheumatology #
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Bleeding / Bruising - Differential ... Sequestration Disordered ... Platelet Function ... • Steroids • Vasculitis ... Algorithm #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
with or without platelet ... cardiac valve, vasculitis ... Consider RBC membrane disorder ... Diagnosis #Algorithm #workup ... #hematology #testing
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
without platelet ... MYH9-Related Disorder ... Defects #comparison #table ... #differential # ... diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Disorders - Differential ... Diagnosis and Workup ... #Disorders #Differential ... Diagnosis #Causes #Workup ... #hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... count and platelet ... 1 or Type 3) — differentiate ... #disorders #hematology ... #hemepath #differential
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Thrombocytopenia - Differential ... Connective tissue disorders ... Thrombocytopenia #Differential ... Diagnosis #Algorithm #hematology ... #platelets
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
Pancytopenia - Differential ... < 1800/uL, • platelet ... /uL Initial Workup ... Diagnosis #Algorithm #hematology ... #workup
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... o CML - bcr-able ... o Other bcr-able ... #hematology #Markers ... #Differential #