13 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... - 80% have fever ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... , breast CA - Hematologic ... Leukemia cutis Diagnosis ... Treatment: - Systemic ... #diagnosis #dermatology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... Actively maintained fever ... hyperthermia crisis (late sign ... Anesthesia #Checklist #Diagnosis ... #Management #Workup
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Subacute-Acute: • Common: fever ... #management #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... Physical Exam/Signs ... microglobulin Treatment ... #workup #oncology ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... following: • Fever ... • Bicytopenia Treatment ... #hematology
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
The signs and symptoms ... ) ▪ Malaise, fever ... Syphilis #Rash #Diagnosis ... #Clinical #Photo ... #Dermatology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
: - Fever + ANC ... full infectious work-up ... days → add fungal work-up ... ): - Hematologic ... Oncology #HemeOnc #Diagnosis
Cryptogenic Organizing Pneumonia - Illness Script

PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Illness Script PATHOPHYSIOLOGY ... Males=Females SIGNS ... Cough, dyspnea, fever ... identified (autoimmune, meds ... , neoplastic) TREATMENT
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
sex • Metabolic syndrome ... 12-24 Hours • Fever ... double contour sign ... +Radiographic signs ... #rheumatology