27 results
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
Cell (Temporal) Arteritis ... old; F>M Signs/Symptoms ... skin lesions ... #Pathophysiology ... #Vasculitis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
and often causes arthritis ... mucositis - Rash ... , arthritis LARGE ... central nervous system ... Symptoms (Sx) in
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... of hip (rare), Arthritis ... erythematosus #signs #symptoms
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis: • Systemic ... Presentation: Systemic ... Symptoms (SX) in ... , mucositis • Rash ... • Progressive symptoms
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... , small-vessel vasculitis ... meningitis), MCC CNS symptoms ... inhibitors • Uveitis- Ophthalmology ... management #signs #symptoms
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
• Psoriatic arthritis ... - with the skin ... Lupus - with Systemic ... should have other symptoms ... like “butterfly rash
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Episcleritis Signs and Symptoms ... symptoms by days ... Leukocytoclastic vasculitis
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
• Polymorphous rash ... : - Coronary Arteritis ... - Generalized Skin ... Criteria #Diagnosis #Pathophysiology ... #Vasculitis
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
inflammatory vasculitis ... required due to skip ... required +/- prompt ophthalmology ... absence of visual symptoms ... Temporal #Signs #Symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
(PBC), or with systemic ... like rheumatoid arthritis ... (RA) or systemic ... Xeroderma (Dry skin ... Sjogrens #Syndrome #Pathophysiology