18 results
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Pancytopenia - Differential ... Diagnosis Congenital ... deficiency • Fanconi’s anemia ... Cancer: • Leukemia ... #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... • Acne • Allergy ... (Pancytopenia, ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... Diagnosis: • Pancytopenia ... to MDS or acute leukemia ... #diagnosis #management ... #treatment #hematology
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
- Differential Diagnosis ... Reactive: • Anemia ... /blood loss (Fe ... Chronic Myeloid Leukemia ... causes #Platelets #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... hemolysis, deficiency anemia ... post-splenectomy, Exercise, Allergic ... #Algorithm #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... the total white blood ... released during an allergic ... #Differential #Diagnosis ... #causes #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
bone marrow + pancytopenia ... virus (EBV) • Leukemia ... result from low blood ... #oncology #hematology ... #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Blast cells - Blood ... - infiltrates (anemia ... #Hematology #Oncology ... #Diagnosis
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Generalized Differential Diagnosis ... / Systemic == Blood ... renal failure/uremia ... • Lymphoma • Leukemia ... #generalized #dermatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... #diagnosis #workup ... #oncology #hematology