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differential management algorithm causes oncology workup anemia skin disorders systemic thrombocytopenia hemolysis monoclonal pancytopenia table treatment aflp atlas autoimmune bleeding
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #hematology #rheumatology ... #nonpalpable #dermatology
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
and Associated Diseases ... Microscopy #Pathology #Hematology ... #Diagnosis #Dyspmorphic ... GrepMed Recommended Text ... Pathologic Basis of Disease
Expected DAT Results in Autoimmune Hemolysis DAT Negative Hemolysis • DAT Poly ( - ), IgG (
Cold agglutinin disease ... #antiglobulin #test ... Autoimmune #Hemolysis #hematology ... #diagnosis
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Drug-associated, PCH, Evans Syndrome ... , Drugs, Liver Disease ... Laboratory Tests ... #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
- Differential Diagnosis ... Congenital Diseases ... Wiskott-Aldrich syndrome ... and Autoimmune Diseases ... #Hematology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
infection • Lyme disease ... Antiphospholipid-antibody syndrome ... Sarcoidosis #dermatology ... #differential #diagnosis ... #rheumatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Myelodysplastic Syndromes ... Liver Function Tests ... Liver Function Tests ... Algorithm #Causes #Hematology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Initial screening test ... block • Sjogren syndrome ... polymyositis overlap syndrome ... #SLE #Summary #diagnosis ... #rheumatology #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... highly inflammatory disease ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology
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