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management differential oncology algorithm acquired activation acute adultonset aki capillary chronic clarksons cll conditions eoe eosinophilic erythematosus extrarticular gastroenteritis hemophagocytic
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
hemopathies, solid cancers ... hepatitis • Pulmonary ... #Disease #diagnosis ... #management #treatment ... #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
LC deposition disease ... • Hematologic ... malignancies Treatment ... #Differential #Diagnosis ... #Classification
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... - Diagnosis and ... thrombocythemia), Autoimmune disease ... adsorption onto cancer ... #treatment #hematology
Eosinophilic Gastroenteritis: Treatment Options Based on Severity of the Disease Mild: • Trial of PPI • Trial
Gastroenteritis: Treatment ... Severity of the Disease ... for HES: • Hematology ... • Additional diagnostic ... #management #gastroenterology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Adult-onset Still ... Hypofibrinogenemia • ↑ PT ↑ PTT ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
infection • Still's ... Pulmonary ... Spondyloarthropathies, SLE • Pulmonary ... #differential #diagnosis ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... Differential Diagnosis ... arthritis, adult-onset Still ... • Cervical cancer ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
B-LNH), solid cancers ... • Autoimmune diseases ... +, Adult-onset Still ... disease, Infection ... #summary #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
: • 10%-15% Pulmonary ... , INC risk PE, Pulmonary ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... #Rheumatology #
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