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differential algorithm management causes hodgkins lymphoma myelodysplastic rheumatology thrombocytosis aplastic comparison dermatology erythematosus ferritin iron lupus monoclonal myelodysplasia nonhodgkins nonpalpable
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential Diagnosis ... -100): • Non-hemolytic ... , CKD • Hemolytic ... Reticulocytosis, MDS ... #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... - Differential Diagnosis ... • Bleeding • Hemolysis ... #MCV #Classification ... Algorithm #Causes #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
• Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Cancer: • Leukemia ... Antibody-mediated hemolysis ... #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
(MD) - Diagnosis ... cytopenias (usually anemia ... #MDS #Diagnosis ... Management #treatment #hematology ... #oncology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
malignancies • Anemia ... , hemolysis, hemorrhage ... Myelodysplastic syndrome ... Chronic myeloid leukemia ... #Causes #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
, GATA2 deficiency ... , CTLA4 deficiency ... virus (EBV) • Leukemia ... #oncology #hematology ... #diagnosis #management
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Anemia - Differential ... extravascular) hemolysis ... Gastrectomy, WHDA syndrome ... Matthew Ho, MD ... #ferritin #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... , deficiency anemia ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... necrosis) • VIT K deficiency ... #hematology #rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
involved) • No leukemic ... HIV, EN, HTLV-1, HCV ... translocation • Types: Classification ... NonHodgkins #comparison #oncology ... #hematology
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