31 results
Hemolytic anemia in Wilson's disease

#Wilsons #Disease #hemolytic #anemia #Hematology #pathophysiology
anemia in Wilson's disease ... #Wilsons #Disease ... hemolytic #anemia #Hematology ... #pathophysiology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Thromboplastin Time (PTT ... inhibitor • Liver disease ... Thromboplastin Time (PTT ... thematttsai #PT #PTT ... Thromboplastin #laboratory #hematology
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver Disease ... Cholangitis #pathophysiology ... #pbc #psc #hepatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
infection, Autoimmune diseases ... - Autoimmune diseases ... Lymphomas • Other hematologic ... Tuberculosis • HIV #Hodgkins ... #differential #hematology
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Is a Systemic Disease ... prolonged #diagnosis #hematology ... mixing #studies #PTT
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Biliary Cirrhosis - Pathophysiology ... female-predominant disease ... of autoimmune disease ... relative with PBC Pathophysiology ... #hepatology
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Sickle Cell Disease ... - Pathophysiology ... of disease and ... #Pathophysiology ... Complications #Hematology
Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease
Increased Thrombosis 
Increased Platelet-Vesset Wall Interaction 
 •
Bleeding in Liver Disease ... Clot #Cirrhosis #Pathophysiology ... #Hepatology #Liver
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Von Willebrand’s disease ... Von Willebrand disease ... Von Willebrand disease ... Acquired: • Liver disease ... Differential #Diagnosis #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT/PTT ... protein C and S Pathophysiology ... PT/INR: ↑ • PTT ... • Severe Liver Disease ... treatment #management #hematology