16 results
diagnosis differential management nephrology sle erythematosus hcq hydroxychloroquine systemic acidosis adverseeffects algorithm ana anca antibodies antibody antineutrophil antinuclear benefits champs
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
• Diabetes • Pituitary ... Insufficiency • Adrenal ... Metabolic • Renal ... Myasthenia Gravis Pharmacologic ... Chronic Fatigue Syndrome
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
• Special cases ... (e.g. renal failure ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... severe disease & renal ... severe disease Treatment ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... antiphospholipid syndrome ... S - Systemic Lupus ... Erythematosus (total 50, renal ... #differential #hematology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
or 0.5 g/day → renal ... severity (ISN/RPS classification ... by 12 months Classification ... Nephritis #Management #treatment ... #management #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... • Sjögren syndrome ... polyangiitis without renal ... ANCA+ 30-60% • Renal-limited ... antibodies #diagnosis #rheumatology
Classification of Diabetes Insipidus Central or neurogenic diabetes insipidus: - Congenital - Structural malformations affecting the hypothalamus
Classification of ... hypothalamus or pituitary ... Acquired - Primary renal ... uropathy, Metabolic causes ... Treatment is aimed
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... of renal or hepatic ... Risks #Benefits #Lupus ... #pharmacology # ... #sideeffects #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Non-autoimmune rheumatologic ... Shrinking lung syndrome ... APLA/LAC: • Renal ... Erythematosus #Diagnosis #Rheumatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
contribution of liver or renal ... - Compartment syndrome ... deficiency - Renal ... lactate production Renal ... #typea #typeb #classification
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