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diagnosis classification management disorders nephrology sle vasculitis apml comparison differentiation druginduced eosinophil eosinophilia erythematosus glomerulonephritis lymphomas lymphoproliferative nonhodgkin oncology pathophysiology
Lupus Nephritis Classification Algorithm #Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis ... #Lupus #Nephritis ... #diagnosis #differential ... #types #rheumatology ... #nephrology #renal
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... disease, Kawasaki, Nephrotic ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... APLA/LAC: • Renal ... : • Symptoms limited ... Erythematosus #Diagnosis #Rheumatology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... or 0.5 g/day → renal ... #treatment #management ... #rheumatology #
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... Nephritis, Cryoglobulinemia ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm ... #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... constitutional symptoms ... • Treatment: ... nephritis, NPSLE ... comparison #table #rheumatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... workup for specific symptoms ... glucocorticoid treatment ... #Differential # ... diagnosis #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... pattern of spread, B symptoms ... Responsive to Treatment ... pathophysiology #Hematology ... #algorithm
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Diagnosis: >3 symptoms ... initiation • Differential ... Failure Treatment ... diagnosis #management #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... inflammation Others: • Lupus ... such as systemic lupus ... Presentation - Systemic Symptoms ... #diagnosis #rheumatology
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