18 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... - Differential Diagnosis ... and Workup History ... #Causes #Workup ... #hematology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... chain IIA • Thrombocytopenia ... #Defects #comparison ... #table #differential ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... hemorrhagic skin lesions ... inflammation • Thrombocytopenia ... : - Thrombocytopenia ... #Differential #Diagnosis
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... Liver tests, Low Platelets ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... Liver tests, Low Platelets ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... - Differential Diagnosis ... hemostasis: - Thrombocytopenia ... - Abnormal platelet ... deficiency Work
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... activity is the diagnostic ... intravascular hemolysis Platelet ... and decreased platelet ... #Workup #Hematology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
TMAs cause MAHA ... triad of MAHA + thrombocytopenia ... Cr>2.3 & platelets ... Microangiopathy #TMAs #hematology ... #diagnosis #ttp
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... patients Skin lesions ... doi: 10.1111/all ... #rheumatology # ... comparison #table
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... count (thrombocytopenia ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology