12 results
diagnosis differential hyperkalemia causes syndrome algorithm chloride diuretics gitelman high management medications renal acidosis alkalosis aniongap classes conversion diuresis druginduced
Drugs that Impair Renal Potassium Excretion Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... Aldosterone Release: ACE ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... Impaired #Potassium
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Chloride Algorithm Cl ... Kidney loss of Cl ... Cystic fibrosis Cl ... of sodium and potassium ... urine #Algorithm #nephrology
Hypochloremia - Differential Diagnosis Algorithm Cause - Decreased Intake: • Low salt in diet • Exclusive D5W
Excessive vomiting - Metabolic ... increase may cause metabolic ... decrease may cause metabolic ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome Pathophysiology ... distal tubule. ↑ Nacl ... → Hypokalemia Metabolic ... Gitelman #Syndrome #Pathophysiology ... #nephrology #diagnosis
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• NSAIDs • ACE ... • Recent IV potassium ... infusions) - Metabolic ... diagnosis #causes #potassium ... #high #nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Non-anion Gap Metabolic ... Potassium-sparing ... ACE-Is and ARBs ... aniongap #NonGap #Metabolic ... diagnosis #causes #nephrology
Diuretics - Pharmacology Thiazides diuretics: • Inhibit Na+ Cl- cotransporter in distal tubule • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... • Inhibit Na+ Cl ... Piretanide Potassium ... #Diuretics #Pharmacology ... #nephrology #conversion
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• NSAIDs • ACE ... • Recent IV potassium ... infusions) - Metabolic ... diagnosis #causes #potassium ... #high #nephrology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
resistance • Metabolic ... Inhibitors of Na+K+2Cl ... Excretion #Diuresis #Nephrology ... #Pharmacology #
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