29 results
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... Agents Subclass, Drug ... Chlorthalidone POTASSIUM-SPARING ... #Medications #Pharmacology ... #summary #table
Diuretic Electrolyte Excretion Effects 
Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid
 - Thiazide Type
Diuretic Electrolyte ... Excretion Effects Diuresis ... +, Mg2+, Ca2+, Cl ... electrolytes #effects #pharmacology ... #comparison #table
Pharmacologic Treatments of Chronic Hypertension in Pregnancy
Central alpha-agonists
 - Methyldopa
 - Clonidine
Combined alpha- and beta-blocker
 -
Pharmacologic Treatments ... Hydralazine - Diuretics ... Management #Treatment #Pharmacology ... #HTN #Table #Drugs
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
RAAS inhibiting drug ... diuretic, which ... , just like all ... RAAS inhibiting drugs ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Thiazides diuretics ... • Inhibit Na+ Cl ... Piretanide Potassium ... #Pharmacology #
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair ... Renal Potassium ... Aldosterone Release: ACE ... Pathophysiology #Pharmacology ... #Impaired #Potassium
Antiseizure Drugs 
Sodium Channel Blockers: Carbamazepine, Oxcarbazepine, Eslicarbazepine, Lamotrigine, Lacosamide, Phenytoin, fosphenytoin
Broad Spectrum: Valproate, Levetiracetam, Brivaracetam,
Antiseizure Drugs ... Tiagabine, Vigabatrin Potassium ... #Antiseizure #Drugs ... medications #epilepsy #pharmacology ... #comparison #table
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
- Potassium depletion ... renal disease Drugs ... : - Loop diuretics ... #medications #drugs ... #pharmacology #
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... pathophysiology #pharmacology ... #potassium #medications
Antihypertensive Drugs - Summary
Diuretics:
 • Thiazide type: Chlorothiazide, Hydrochlorothiazide
 • Thiazide-like: Chlorthalidone, Indapamide, Metolazone
 • Loop
Antihypertensive Drugs ... - Summary Diuretics ... Metolazone • Loop diuretics ... Sympatholytic Drugs ... medications #summary #table