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Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... underlying liver disease ... #Acute #Chronic ... Cirrhosis #Hepatology #gastroenterology
ACE Trial: Randomized controlled trial of Ceftriaxone and doxycycline, with or without metronidazole, for the treatment
metronidazole, for the treatment ... of acute PID Wiesenfeld ... , et al. 2020. ... ID #Infectious Diseases ... #inflammatory #disease
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... LC deposition disease ... malignancies Treatment ... #AKI #Cancer #Oncology ... #Differential #
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
Treatment Schema ... Standard-Risk Acute ... Cytarabine #ALL ... #Acute #Lymphoblastic ... #timeline #oncology
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Lysis Syndrome An acute ... spontaneously (before any treatments ... grade lymphoma & Acute ... malignancies Treatments ... Syndrome #TLS #oncology
Causes of acute intestinal obstruction:
-Adhesive disease
-Neoplasm 
-Herniation
-IBD
-Volvulus 
-Other

#Clinical #IntestinalObstruction #Differential #Surgery #Gastroenterology
Causes of acute ... obstruction: -Adhesive disease ... IntestinalObstruction #Differential ... #Surgery #Gastroenterology
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
of Sickle Cell Disease ... Acute sickle cell ... Supportive with treatment ... #SickleCell #Disease ... hepatology #hepatitis #differential
Acute and Chronic Causes of Dyspnea - Differential Diagnosis
Pulmonary/Chest Wall:
 • Acute: Trauma, COPD exacerbation, Asthma
Causes of Dyspnea - Differential ... : ACS, Acute decompensated ... Neuromuscular disease ... Mitochondrial disease ... Chronic #Causes #Differential
The Diagnostic Approach to Hyperkalemia
Drugs
 - Amiloride
 - Spironolactone
 - Triamterene
 - Trimethoprim
 - Pentamidine
 -
Tubulointerstitial diseases ... - Sickle cell disease ... LMW heparin - ACE-I ... Diabetes mellitus - Acute ... Algorithm #diagnosis #differential
Medical Management of Acute RV Failure
 • Evaluate and Treat Etiology of RV Failure [e.g. Acute
Management of Acute ... Acute Myocardial ... Concomitant Pericardial Disease ... Supportive Measures Act ... cardiology #management #treatment