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management differential rheumatology causes abscess acquired activation algorithm antibodies associations autoantibodies cardiology cerebritis chf clinical cns coagulation criticalcare crystals deficiencies
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Malabsorption (e.g ... warfarin, DOACs (e.g ... Autoimmune disorders (e.g ... #comparison #diagnosis ... #hematology #deficiency
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... - Diagnosis and ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... #treatment #hematology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
La) - Sjogren's syndrome ... - Vasculitis, e.g ... - Vasculitis, e.g ... Associations #diseases #diagnosis ... #table #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
organ damage • Treatment ... Low calcium • Treatment ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... permeability Diagnosis ... Lumbar Puncture, EEG ... Treatment: ... #cerebritis #diagnosis
Urine Microscopy Crystals Uric Acid crystals: - Formation promoted by acidic urine - Seen in tumor lysis
in tumor lysis syndrome ... urease-producing organisms (e.g ... acidic urine - Diagnostic ... Microscopy #Crystals #comparison ... #table #urinalysis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
underlying disease (eg ... • Infection (eg ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
antibiotics once stable ... hemorrhage • Treatment ... shows a small, stable ... residual lesion or is clear ... • Vasculitis (e.g
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
• A clinical diagnosis ... and lower jaw Treatment ... antiinflammatory properties e.g ... diagnosis #management ... #Dermatology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... heparinized tube) • ECG ... test (only if no clear ... Elimination (see Table ... #Hyperkalemia #Diagnosis
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