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differential causes algorithm management hyponatremia intercellularshift treatment acute gitelman hypernatremia hyperreflexia hypokalemia hyporeflexia hypotonic k kidneyinjury pathophysiology physiologic potassium rhabdomyolysis
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
: Hypovolemia, Hypervolemia ... Cirrhosis, Nephrotic syndrome ... #differential #diagnosis ... #table #sodium ... #nephrology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
Kidney Injury AKI ... - Differential Diagnosis ... Impaired forward flow ... inhibitors, hepatorenal syndrome ... #nephrology
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... - Differential Diagnosis ... EABV (e.g., CHF ... renal failure • AKI ... IntercellularShift #Nephrology
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia Focal Hyporeflexia: • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Hyporeflexia: • Hypercalcemia ... polyneuropathy (e.g ... Guillain-Barré syndrome ... #differential #diagnosis ... #table #neurology
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
- Differential Diagnosis ... • Euvolemic (Low ... , Cushing syndrome ... Workup #Algorithm #nephrology ... #sodium
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... declines > ALT) • AKI ... + myoglobin AKI ... per day until stable ... causes #treatment #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... , RTA Type IV, AI ... Elimination (see Table ... acidosis) • Low ... Treatment #potassium #nephrology
Hyponatremia - Differential Algorithm Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP Hypotonic Hyponatremia: • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
polydipsia • Hypervolemia ... Cirrhosis, Nephrotic Syndrome ... Differential #Algorithm #diagnosis ... #causes #nephrology ... #sodium #low
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... • Unexplained hypokalemia ... alkalosis • Normal or low ... #diagnosis #nephrology
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... , TTKG, distal flow ... • Cell Lysis (e.g ... Tumor Lysis Syndrome ... IntercellularShift #Nephrology
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