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diagnosis hematology algorithm causes hemolytic classification extravascular intravascular workup evaluation hodgkins lymphoma management nonpalpable oncology palpable rheumatology schistocytes testing thrombocytopenia
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... syndrome (ST-HUS ... known as atypical HUS ... anemia" • HELLP ... #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... thrombocytopenic purpura ... uremic syndrome (HUS ... Extravascular #Causes #differential ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential ... anemia • ... MAHA (TTP, DIC, HUS ... Extravascular #Differential ... Algorithm #Causes #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic ... anemia - Splenomegaly ... : • DIC, TTP/HUS ... #Differential #
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... DIC, TTP, HELLP, HUS ... #Anemia #Differential ... Algorithm #workup #hematology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. TTP/HUS indicates thrombotic
TTP/HUS indicates ... thrombocytopenic purpura ... /hemolytic uremic ... thrombocytopenia, Hematology ... #Diagnosis #Differential
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... • MAHA: TTP, HUS ... #Anemia #Differential ... classification #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... - MAHA: TTP, HUS ... Defects: Sickle cell anemia ... #Differential # ... Diagnosis #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Thrombocytopenic Purpura ... result in severe anemia ... anemia Indirect ... WBC count and differential ... Diagnosis #Workup #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
persons • It has ... Weight loss • Anemia ... nodosum • Immune hemolytic ... anemia • Pain ... Immunohistochemical studies (to differentiate
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