48 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
to GBM disruption ... Proteinuria often ... Massive proteinuria ... Classification #Proteinuria ... #Nephrology #Diagnosis
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... hematuria and/or proteinuria ... nephrotic/nephritic syndromes ... Nephritic #Nephrotic #Syndrome ... Comparison #Algorithm #Nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Algorithm Persistent Proteinuria ... • Fanconi's syndrome ... proliferative • Anti-GBM ... #Nephrology #Differential
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
and Nephritic Syndrome ... - Normal/low Proteinuria ... pressure - Raised Proteinuria ... edgarvlermamd - Nephrology ... Comparison #Table #Nephrology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal Syndrome ... Pulmonary Renal Syndromes ... • Urinalysis (proteinuria ... anti-ANCA ab, anti-GBM ... differential #diagnosis #nephrology
Albuminuria (Grades) and Risk for CKD
Normal to mildly increased albuminuria:
 - Albumin excretion rate: < 30
Nephrotic-range proteinuria ... nephrotic range proteinuria ... defined as nephrotic syndrome ... classification #CKD #nephrology ... #diagnosis #proteinuria
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
glomerular bleeding (proteinuria ... → Refer to Nephrology ... cystoscopy • Refer ... to Nephrology if
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
overt glomerular proteinuria ... Cytomegalovirus; GBM ... hemolytic-uremic syndrome ... #nephrotic #syndrome ... #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
disease (hematuria, proteinuria ... Basement Membrane (GBM ... Linear, ribbon-like GBM ... staining on IF • No EM ... Differential #Diagnosis #Nephrology
Urine Specific Gravity - Interpretation
Specific Gravity = Density of urine / Density of water
SG close to
Dehydration • SIADH (syndrome ... Glycosuria • Proteinuria ... #differential #nephrology