46 results
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Pruritus - Generalized ... Cholestatic liver disease ... Myelodisplastic syndrome ... Psychiatric Disease ... #generalized #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
associated with pruritus ... reticularis Differential ... • Goodpasture syndrome ... Polyangiitis #GPA #dermatology ... rash #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
infection • Lyme disease ... migrans • Lyme disease ... Sarcoidosis • Crohn's disease ... Antiphospholipid-antibody syndrome ... #rashes #differential
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary ... Skin Lesion - Differential ... Cholestatic liver disease ... Myelodisplastic syndrome ... #generalized #dermatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Associated with skin ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Hydroxychloroquine *Short ... #management
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
- Differential ... Vasculitis: • Behcet Disease ... • Cogan syndrome ... #dermatology #rheumatology ... #differential #
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment
Stop offending agents:
 • List as allergies
Symptoms (DRESS) Syndrome ... , IVIG etc • Skin ... antihistamine for pruritis ... #Treatment #Management ... #dermatology
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... appearing during the disease ... #differential # ... diagnosis #dermatology ... oncology #clinical #skin
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Vasculopathy #Purpura #Differential
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Arthralgia/arthritis, Skin ... fraction < 20% Differential ... #diagnosis #management ... #treatment #rheumatology