17 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... • Exogenous (KCL ... #differential #diagnosis ... #pathophysiology ... #pharmacology #
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... complete paralysis of all ... Diagnosis: • ... Barre #Syndrome #diagnosis
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... and iron release Diagnosis ... analyses showed reduced ... composite endpoint of all-cause ... #heartfailure #diagnosis
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Heparin Induced ... Thrombocytopenia (HIT) - Diagnosis ... ♀, ↑Age, ESRD Pathophysiology ... Management: • D/c all ... #HIT #Heparin #Induced
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
Chlorpromazine ACh ... Block action of ACh ... irreversible • Drug induced ... #SideEffects #pharmacology ... #diagnosis #psychiatry
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... complete paralysis of all ... bulbar muscles DIAGNOSIS ... the underlying pathophysiology ... SinaiBmoreIMRes #GBS #Guillain
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
un lymphatic Diagnostic ... endomyocardial biopsy Pharmacology ... : • ACE Inhibitors ... #heartfailure #diagnosis ... management #cardiology #pharmacology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
- Differential Diagnosis ... and Pathophysiology ... deficiency anemia (reduced ... • Mitchell et al ... #Pathophysiology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential Diagnosis ... considered in all ... Hyperhomocysteinemia - Heparin-induced ... Venous #Arterial #pathophysiology ... #differential #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... ATRA treatment Pathophysiology ... endothelial damage • Induce ... opacities • Diagnosis ... • Differential Diagnosis