12 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... Angiotensin-converting enzyme (ACE ... #differential #diagnosis ... pathophysiology #pharmacology ... #potassium #medications
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... Aldosterone Release: ACE ... happypillsrx/ #Hyperkalemia ... Pathophysiology #Pharmacology ... #Impaired #Potassium
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Diagnosis Framework ... • NSAIDs • ACE ... • Recent IV potassium ... Medications 2. ... #causes #potassium
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
- Differential Diagnosis ... Sarcoidosis • Hypercalcemia ... drugs • ACE ... #Differential #Diagnosis ... #Algorithm #endocrinology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Diagnosis Framework ... • NSAIDs • ACE ... • Recent IV potassium ... Medications 2. ... #causes #potassium
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
) MECHANISM: Potassium ... patiromer) is a potassium ... ACE inhibitors, ... Veltassa #Patiromer #Potassium ... #Pharmacology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Hypokalemia ... Hyperkalemia ... Potassium-sparing ... ACE-Is and ARBs ... #differential #diagnosis
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Etiology: • Medications ... STOP offending medications ... Ca-gluconate or 1g CaCl ... #Treatment #potassium
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Causes of Hyperkalemia ... Angiotensin-converting enzyme (ACE ... combination with ACE ... #Differential #Diagnosis ... #High #Potassium
Pragmatic diagnostic algorithm for hypokalemia. 
***Typical presentations: 
 • Vomiting: urine Na/Cl > 1.6, low urine
Pragmatic diagnostic ... algorithm for hypokalemia ... correcting serum potassium ... Other medications ... #diagnosis #differential